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True Dough

(24,919 posts)
Wed Oct 29, 2025, 08:05 AM Wednesday

Potential major breakthrough in treating cancer



Massimo
@Rainmaker1973

A single dose of a new cancer drug made a brain tumor almost disappear – in just five days.

Doctors at Massachusetts General Hospital reported “dramatic and rapid” tumor regression in the first patients treated with a next-generation form of CAR T-cell therapy for glioblastoma, one of the most aggressive brain cancers known.

The therapy, called CARv3-TEAM-E, was developed to overcome a major hurdle in treating solid tumors: their ability to hide from the immune system.

The personalized treatment reprograms a patient’s immune cells to attack the tumor, and in one extraordinary case, nearly eliminated the cancer within just five days. This novel therapy is designed to target multiple features of the tumor at once, a strategy that may help overcome the common challenge of treatment resistance in solid tumors like glioblastoma.

Although the tumors eventually returned, the early outcomes were described as unprecedented. One patient saw a 60% reduction in tumor size that lasted for half a year—an impressive result in a cancer known for its aggressiveness.

The trial’s success marks a major step forward for immunotherapy in brain cancer and raises new hopes for long-term control or even a cure. Researchers are now working to refine the treatment and extend its effects, with the ultimate goal of turning a once-terminal diagnosis into a survivable condition.




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Potential major breakthrough in treating cancer (Original Post) True Dough Wednesday OP
This is happening despite the funding obstacles created by the current administration True Dough Wednesday #1
That is a damn miracle. Science is a miracle. Scrivener7 Wednesday #2
K & R................... Lovie777 Wednesday #3
As an oncology nurse, I wish people would understand how close we are to travelingthrulife Wednesday #4
Extraordinary! Wonderful! I lost a dearest friend to a glioblastoma. It's a devastating diagnosis. Nanjeanne Wednesday #5
This makes me happy for future cancer patients but EuterpeThelo Wednesday #6
Science paleotn Wednesday #7
Our current administration sure has a lot of uninformed opinions KS Toronado Wednesday #8
DUPE bif Wednesday #9

True Dough

(24,919 posts)
1. This is happening despite the funding obstacles created by the current administration
Wed Oct 29, 2025, 08:11 AM
Wednesday

Absolute morons!

travelingthrulife

(3,662 posts)
4. As an oncology nurse, I wish people would understand how close we are to
Wed Oct 29, 2025, 09:01 AM
Wednesday

treatments that will be much more specific and less traumatic for people with cancer. Now is not the time to back down on research.

Nanjeanne

(6,434 posts)
5. Extraordinary! Wonderful! I lost a dearest friend to a glioblastoma. It's a devastating diagnosis.
Wed Oct 29, 2025, 09:02 AM
Wednesday

EuterpeThelo

(91 posts)
6. This makes me happy for future cancer patients but
Wed Oct 29, 2025, 11:03 AM
Wednesday

it's too late for my fierce and beautiful mama, who we lost to stage 4 glioblastoma in 2021. It took her in less than six months from the date of diagnosis, even with surgery, chemo and radiation.

Then again, I don't have to see the horrible emotional and spiritual pain she would be in watching what is going on in the world right now.

paleotn

(21,086 posts)
7. Science
Wed Oct 29, 2025, 11:05 AM
Wednesday

No Josh Rogan and ivermectin memes required. I do wish we would go back to the days when uninformed opinion was considered exactly that. And the untrained hoi polloi deferred to those who fucking know things.

KS Toronado

(21,765 posts)
8. Our current administration sure has a lot of uninformed opinions
Wed Oct 29, 2025, 12:44 PM
Wednesday

From ivermectin & autism and now water kills magnets. ..

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